<p>What You Will Contribute To Altos</p> <p>At Altos, your work will be at the heart of a mission to transform medicine by reversing disease and restoring cell health. You will contribute to the development of a new generation of drugs rooted in an advanced understanding of cellular rejuvenation and resilience.</p> <p>As a Sr Scientist of Discovery Pharmacology team, your primary focus will be supporting the in vitro pharmacology needs of the Drug Discovery and Development (3DS) division of Altos. This is a laboratory research scientist position focused on the development and execution of cell-based and biochemical assays, and complex in vitro models. Your work will contribute to our drug discovery campaigns across a diverse portfolio of drug discovery and development stage projects. Your expertise will be instrumental in driving our mission and making a significant impact in aging/rejuvenation biology and drug discovery.</p> <p>Responsibilities</p> <ul> <li>Investigate and validate drug targets, define mechanisms of action (MoA) through robust pharmacology strategies. </li><li>Design, automate, and troubleshoot all kinds of assays. </li><li>Analyze data and present it to help make project decisions. </li><li>Keep great records in the electronic lab notebook (ELN), ensure reproducibility and data integrity. </li><li>Work with people across different teams, including the Product Development crew. </li></ul> <p>Who You Are</p> <p>Required Qualifications</p> <ul> <li>A Ph.D. (Pharmacology, Bio, etc.) plus at least 6 years of post-PhD experience AND 3+ years industry experience in drug discovery and development. </li><li>You need to be able to design your own experiments and get solid, repeatable results. </li><li>Major experience with cellular and biochemical assays and complex in vitro models. </li><li>You must be a pro with lab automation and high-throughput techniques (think Bravo, Echo, I.DOT, and tech like MSD, HTRF, AlphaLISA). </li><li>Good communication skills and you're fast, organized, and can handle a lot. </li><li>Experience working with outside labs (CROs) is also required. </li></ul> <p>Preferred Qualifications</p> <ul> <li>Experience with high-content imaging in high-throughput settings (96- and 384-wells). </li><li>Worked with different drug types (small molecules, nucleic acids, gene therapies). </li><li>Knowledge of aging/rejuvenation biology is a huge plus. </li><li>Screening experience with various modalities (small molecules, siRNA, ASO). </li><li>Familiarity with microfluidics assays. </li></ul> <p>The salary range for Redwood City, CA:</p> <ul> <li>Senior Scientist I, In Vitro Pharmacology $176,000 - $225,700 </li></ul> <p>Exact compensation may vary based on skills, experience, and location.</p> <p>For UK applicants, before submitting your application:</p> <ul> <li>Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice) </li><li>This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment. </li></ul> <p>#LI-NN1</p>