<p>About the Job</p> <p>The Nguyen Lab is currently developing small molecule probes, biochemical, cell biological and genetic approaches to investigate the underlying DNA damage response mechanisms in cancers. One area of active research is to investigate mechanisms of sensing and resolving R-loops in cancers to provide molecular insight for the development of new targeted cancer therapeutic approaches. Research technicians are responsible for performing standard bench-level laboratory experiments in support of scientific research.</p> <p>Responsibilities:</p> <p>100% Laboratory research</p> <ul> <li>Perform experiments at the bench level to support investigative work (DNA/RNA isolation and analysis, protein isolation and SDS-PAGE analysis, standard molecular biology techniques) </li><li>Perform and modify documented protocols and assays </li><li>Maintain laboratory records and compile data on experiments and assays </li><li>Interpret and report on experimental results </li><li>Perform statistical analysis of test results and prepare written reports on work performed </li><li>Participate in lab meetings and journal clubs </li><li>May supervise other trainees in the laboratory. </li></ul> <p>A successful candidate will have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction and to follow directions, good organizational skills and the ability to work and think independently. The candidate must have a track record of reliability and good verbal and written communication skills. This is an ideal position for a recent graduate with an PhD, MD/PhD degree in related fields, but not limited to, such as Biochemistry and Molecular Biology, Cancer Biology, and Pharmacology.</p> <p>Qualifications</p> <p>Required qualifications:</p> <ul> <li>PhD or MD/PhD degree in biochemistry, biology, pharmacology, or related fields is required. Must have scientific knowledge in the area of research. </li><li>DNA manipulation, generation, purification, and analysis: PCR, DNA cloning, bacterial transformation, and plasmid isolation and purification. DNA analysis such as DNA gel electrophoresis and analyzing DNA sequencing results/ </li><li>Western blot techniques: SDS-PAGE gel electrophoresis and western blot. </li><li>Co-immunoprecipitation and ChIP </li></ul> <p>Routine mammalian cell culture, transfection using sterile techniques.</p> <p>Preferred qualifications:</p> <ul> <li>Immunofluorescence microscopy: sample preparation, immunofluorescent microscopy experience, image analysis using ImageJ. </li><li>Bioinformatics is highly desirable. </li><li>Statistical data analysis and data analysis. </li></ul> <p>About the Department</p> <p>The Masonic Cancer Center (MCC) is an NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of Minnesota and the surrounding region. Since the time of the first award in 1997, there has been consistent growth of the membership and research base, enabling our center to further advance our knowledge and enhance care for our catchment area. We are driven to be the choice academic healthcare environment for patients, clinicians, scientists and students who seek exceptional, compassionate, precision cancer therapy; innovative clinical trials and prevention programs; cutting-edge research opportunities; and outstanding advanced education.</p> <p>Pay and Benefits</p> <p>Pay Range: $61,008 - $63,000; depending on education/qualifications/experience</p> <p>Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.</p> <ul> <li>Competitive wages, paid holidays, and generous time off </li><li>Continuous learning opportunities through professional training </li><li>Medical, dental, and pharmacy plans </li><li>Healthcare and dependent care flexible spending accounts </li><li>University HSA contributions </li><li>Disability and life insurance </li><li>Employee wellbeing program </li><li>Financial counseling services </li><li>Employee Assistance Program with eight sessions of counseling at no cost </li></ul> <p>How To Apply</p> <p>Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.</p> <p>Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.</p> <p>To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.</p> <p>Diversity</p> <p>The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.</p> <p>The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu</p> <p>Employment Requirements</p> <p>Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.</p> <p>About the U of M</p> <p>The University of Minnesota, Twin Cities (UMTC)</p> <p>The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.</p> <p>At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).</p>