<p>About Stoke:</p> <p>Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights</p> <p>STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals.</p> <p>Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach.</p> <p>Position Purpose:</p> <p>Stoke is seeking a highly motivated and experienced Executive Assistant to join a company pioneering genetic disease treatments. This is a pivotal executive support role for someone who brings composure, precision, and a genuine commitment to enabling leadership excellence at the highest level. The successful candidate will provide direct support to the Chief Patient Officer, and SVP, Head of Global Medical Affairs.</p> <p>Key Responsibilities:</p> <ul> <li>Provide proactive, comprehensive, and confidential administrative support to the heads of the Commercial and Medical Affairs organizations and their teams, ensuring seamless coordination across calendars, meetings, and business priorities. </li><li>Partner with the executives' direct teams as needed to facilitate communication, scheduling, and information flow-providing occasional administrative support to ensure alignment and efficiency across functions. </li><li>Manage complex domestic and international travel logistics, including itineraries, accommodations, and expense reconciliation. </li><li>Find cost effective solutions while maintaining high standards for travel and events for the entire team </li><li>Plan offsite activities by assisting in agenda creation, coordinating internal and external speakers, and partnering with IT for technical event needs </li><li>Manage travel, expenses, meeting planning and invoicing for team events </li><li>Coordinate and support complex meetings with internal stakeholders and Key Opinion Leaders, investors, and other external parties. </li><li>Prepare and organize meeting materials, including agendas, presentations, and follow-up documentation for internal and external stakeholders </li><li>Arrange or set-up AV for hybrid, remote, or in-person meetings and trouble-shoot basic AV technology issues for conference calls and interface with IT and conference services for advanced matters. </li><li>Process and reconcile expense reports promptly and accurately. </li><li>Serve as a liaison and travel coordinator for departmental visitors. </li><li>Create, manage and track purchase orders as requested. </li><li>Provide cross-coverage and proactive collaboration within the administrative team. </li><li>Assist the administrative team on company-wide projects as requested. </li><li>Handle additional special projects as assigned. </li></ul> <p>Required Skills & Experience:</p> <ul> <li>Bachelor's degree required with a minimum of 8+ years relevant experience. </li><li>Experience working in a Biotech environment preferred. </li><li>Extensive experience managing executive travel. </li><li>Proficiency in MS Office with expertise in Microsoft Word, PowerPoint and Excel. </li><li>Detail oriented, flexible and comfortable working in a fast-paced office environment. </li><li>Exceptional verbal and written communication skills. </li><li>Superior organizational skills and dedication to completing projects with quality and in a timely manner. </li><li>Prior experience working with field teams preferred. </li><li>Must be a solution-oriented team player. </li><li>Must possess forward thinking skills, problem solving, creativity and critical thinking skills. </li><li>Ability to maintain high level discretion and confidentiality. </li></ul> <p>Location(s):</p> <p>This position is a hybrid position with an office setting based in Bedford, MA location.</p> <p>Travel:</p> <p>This position will require approximately 5% travel.</p> <p>Compensation & Benefits:</p> <p>At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program.</p> <p>The anticipated salary range for this role is $109,000 - $132,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation.</p> <p>Our benefits package includes medical, dental and vision insurance; life, long and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).</p> <p>Culture & Values:</p> <p>At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.</p> <p>Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do.</p> <p>Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center:</p> <p>https://www.stoketherapeutics.com/careers/</p> <p>For more information, visit https://www.stoketherapeutics.com/.</p> <p>All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.</p> <p>Stoke participates in E-Verify.</p>