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6 days
Not Specified
Not Specified
$28.64/hr - $56.75/hr (Estimated)
<p>AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.</p> <p>Job Description</p> <p>Purpose:</p> <p>We are seeking a highly motivated and collaborative individual with deep expertise in the LNP field to lead our non-viral delivery efforts. This person will report to the Sr Director, Head of Genetic Medicine, and join the Genetic Medicine leadership team. The successful candidate will lead a group of approximately 10 Scientists and be responsible for delivering a pipeline of mRNA/LNP development candidates in close collaboration with biotherapeutics, bioconjugation, protein science, therapeutic area and development teams.</p> <p>Responsibilities:</p> <ul> <li>Lead an internal team of experienced scientists and oversee the design, optimization and production of mRNA and targeted LNP to support in vitro and in vivo studies. </li><li>Define and implement strategies to develop novel LNP formulations and advance targeted LNP delivery by leveraging internal expertise in lipid chemistry, antibody engineering and bioconjugation for in situ mRNA delivery. </li><li>Establish and drive productive collaborations with internal multi-disciplinary project teams and external partners to achieve key milestones. </li><li>Stay up to date on latest development in LNP and other non-viral delivery technologies. </li><li>Dive deeply into science and present scientific findings internally and externally. </li><li>Mentor and coach staff to ensure the team achieve strategic priorities. </li></ul> <p>Qualifications</p> <ul> <li>PhD in biochemistry, chemical engineering, material science or related field. </li><li>> 10 years postdoc/industry experience focusing on lipid nanoparticle systems for mRNA delivery. </li><li>Strong experience in lipid chemistry, formulation development and analytical techniques. </li><li>Deep understanding of conjugation chemistry. </li><li>Experience in mRNA/LNP scale up production and process development. </li><li>Demonstrated ability to lead a high performing team working in a fast-paced environment. </li><li>Proven ability to work collaboratively across teams to meet project deliverables and timelines </li><li>Strong communication and decision making skills. </li><li>Previous experience in targeted LNP for extra hepatic delivery is highly preferred. </li></ul> <p>Prior experience in leading or co-leading a portfolio project to the stage of candidate selection is highly preferred.</p> <p>Additional Information</p> <p>Applicable only to applicants</p>
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