<p>Site: The General Hospital Corporation</p> <p>Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.</p> <p>Job Summary</p> <p>The Rivera laboratory is part of the MGH Pathology Department and MGH Cancer Center and we are also affiliated with the Broad Institute. Our work is focused on using genomic technologies to identify and characterize abnormal gene regulation pathways that drive cancer cells and new approaches to modulate them. Our studies involve the integration of biochemistry, cell biology and genome-wide profiling of chromatin and transcriptional states (such as ChIP-seq, ATAC-seq, RNA-seq, Hi-ChIP and HiC). Using these approaches, our laboratory has uncovered gene regulation networks and new mechanisms of chromatin regulation in a variety of tumor types, including medulloblastoma (Boulay et al, Cancer Discovery 2017) and Ewing sarcoma (Riggi et al, Cancer Cell 2014; Boulay et al, Cell 2017). We have also developed new technologies to study chromatin states associated with repetitive elements and disordered proteins (Tak et al, Cell Genomics 2022; Xing et al, Nature Biotechnology 2023. Research technicians will join a collaborative group of scientists working on cutting edge research.</p> <p>As members of the team, research technicians are expected to work closely with postdoctoral fellows and contribute experimentally to one or several research projects in the laboratory. Contributions will include: setting up and performing experiments, assisting with hypothesis generation, experimental design and data interpretation. Common assays include western blotting, qPCR, cloning, RNA/DNA isolation, genomic assays (e.g. ChIP-seq, RNA-seq), lentivirus production, general mammalian cell culture, compound screening.</p> <p>Qualifications</p> <p>Education</p> <p>Bachelor's Degree Biology required</p> <p>Can this role accept experience in lieu of a degree?</p> <p>No</p> <p>Licenses and Credentials</p> <p>Experience</p> <p>Prior laboratory experience, either through academic coursework, internships, or employment. 1-2 years preferred</p> <p>Knowledge, Skills and Abilities</p> <ul> <li>Strong theoretical and practical knowledge of laboratory techniques and procedures. </li><li>Familiarity with common laboratory equipment and instruments used in research experiments. </li><li>Proficiency in data collection, analysis, and scientific software tools. </li><li>Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively. </li><li>Strong problem-solving skills and the ability to troubleshoot technical issues. </li><li>Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges. </li></ul> <p>Additional Job Details (if applicable)</p> <p>Physical Requirements</p> <ul> <li>Standing Frequently (34-66%) </li><li>Walking Frequently (34-66%) </li><li>Sitting Occasionally (3-33%) </li><li>Lifting Frequently (34-66%) 35lbs+ (w/assisted device) </li><li>Carrying Frequently (34-66%) 20lbs - 35lbs </li><li>Pushing Occasionally (3-33%) </li><li>Pulling Occasionally (3-33%) </li><li>Climbing Rarely (Less than 2%) </li><li>Balancing Frequently (34-66%) </li><li>Stooping Occasionally (3-33%) </li><li>Kneeling Occasionally (3-33%) </li><li>Crouching Occasionally (3-33%) </li><li>Crawling Rarely (Less than 2%) </li><li>Reaching Frequently (34-66%) </li><li>Gross Manipulation (Handling) Frequently (34-66%) </li><li>Fine Manipulation (Fingering) Frequently (34-66%) </li><li>Feeling Constantly (67-100%) </li><li>Foot Use Rarely (Less than 2%) </li><li>Vision - Far Constantly (67-100%) </li><li>Vision - Near Constantly (67-100%) </li><li>Talking Constantly (67-100%) </li><li>Hearing Constantly (67-100%) </li></ul> <p>Remote Type</p> <p>Onsite</p> <p>Work Location</p> <p>149 Thirteenth Street Building 149</p> <p>Scheduled Weekly Hours</p> <p>40</p> <p>Employee Type</p> <p>Regular</p> <p>Work Shift</p> <p>Day (United States of America)</p> <p>EEO Statement:</p> <p>The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.</p> <p>Mass General Brigham Competency Framework</p> <p>At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.</p>