<ul> <li>Job title Sr. Scientist, In vivo Pharmacology Aging and Metabolism </li><li>Function Discovery & Pre-Clinical/Clinical Development </li><li>Sub function Pharmacology </li><li>Category Senior Scientist, Pharmacology (ST6) </li><li>Location Spring House / United States of America </li><li>Date posted May 13 2025 </li><li>Requisition number R-012523 </li><li>Work pattern Fully Onsite </li></ul> <p>This job posting is anticipated to close on May 21 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.</p> <p>Description</p> <p>At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com</p> <p>Job Function:</p> <p>Discovery & Pre-Clinical/Clinical Development</p> <p>Job Sub Function:</p> <p>Pharmacology</p> <p>Job Category:</p> <p>Scientific/Technology</p> <p>All Job Posting Locations:</p> <p>Spring House, Pennsylvania, United States of America</p> <p>Job Description:</p> <p>About Innovative Medicine:</p> <p>Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.</p> <p>Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.</p> <p>Learn more at https://www.jnj.com/innovative-medicine</p> <p>We are searching for the best talent for a Sr. Scientist, In vivo Pharmacology Aging & Metabolism to be in Spring House, PA.</p> <p>Purpose:</p> <p>The Senior Scientist plays a critical role in advancing strategic research initiatives focused on aging-related pathogenesis. This position integrates expertise in drug discovery, metabolic and inflammatory pathways, and translational research to address degenerative diseases, including cardiovascular conditions and sarcopenic obesity. Additionally, the role contributes to broader J&J therapeutic strategies across neuroscience, immunology, and oncology in support of age-related pathologies.</p> <p>You will be responsible for:</p> <ul> <li>Conduct scientific and experimental research to investigate pathways implicated in age-related pathogenesis, including cardiovascular disease, thrombosis, sarcopenia, and energy balance regulation. </li><li>Design and execute preclinical studies, leveraging expertise in in vivo and ex-vivo animal models of cardiovascular disease, thrombosis, obesity, and sarcopenia. </li><li>Collaborate effectively within the internal cardiopulmonary team, including biologists, technical personnel, and clinicians, as well as cross-functional and external research partners. </li><li>Devote approximately 90% of time to laboratory-based research while ensuring seamless integration with broader strategic objectives. </li><li>Provide preclinical support for the regulatory filing of macitentan 75 in pulmonary arterial hypertension as needed. </li></ul> <p>Qualifications / Requirements:</p> <p>Education:</p> <ul> <li>Bachelor's degree is required </li><li>Master's degree or PhD is preferred </li></ul> <p>Required:</p> <ul> <li>Minimum of 4-6 years' experience working with preclinical models of metabolic and cardiovascular diseases in the Pharmaceutical or Biotechnology industry </li><li>Strong communication skills </li><li>Excellent knowledge of standard office software (e.g., Outlook, MS office, etc.,) and other computer systems and technologies (e.g., Zoom/Teams, SharePoint, etc.,) </li><li>Ability to work effectively independently and collaborate in a global team environment </li><li>Ability and willingness to work in a global matrix environment with cross-functional, international teams </li><li>Ability to think dynamically, with a strong attention to detail and problem-solving abilities </li><li>Travel up to 10% of the time (domestic and international), defined by business needs </li></ul> <p>Preferred:</p> <ul> <li>Large pharma in vivo pharmacology </li><li>Publications record in metabolic and CV indications </li></ul> <p>Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.</p> <p>Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.</p> <p>#Li-Onsite</p>