<p>Working at Yale means contributing to a better tomorrow. Whether you are a current resident of our New Haven-based community- eligible for opportunities through the New Haven Hiring Initiative or a newcomer, interested in exploring all that Yale has to offer, your talents and contributions are welcome. Discover your opportunities at Yale!</p> <p>Salary Range</p> <p>$61,500.00 - $91,875.00</p> <p>Overview</p> <p>Carries out research assignments for a large or multi-faceted research project. Performs independent research, experiments, and laboratory techniques. Responsible for the daily operation of a specialized laboratory within a department, and related data analysis for research projects.</p> <p>The goal of the Kueh lab's research is to elucidate the molecular circuits underlying immune cell development and function, and to harness this understanding to engineer immune cells as next generation living therapies. This position will support ongoing research seeking to elucidate the molecular parts, dynamics and function of these circuits, and will involve the execution of experiments including in vitro differentiation assays, bulk and single-cell transcriptomic sequencing, and epigenomic profiling. In addition to pursuing experimental research, responsibilities include day-to-day operations to maintain the laboratory, including maintenance of the mouse colony. The selected candidate will join a dynamic and exciting research team and this position that will allow the candidate to build their laboratory and scientific skills. Essential duties include harvest, isolation and culture of primary immune cells from mice and human; in vitro differentiation assays; flow cytometry; single-cell transcriptomics and chromatin accessibility assays; recombinant DNA cloning; retroviral packaging and transduction; and mouse colony management. General Laboratory: Prepare stocks of some laboratory solutions and help to keep the lab outfitted with supplies and reagents. Data Records: Ensures data results are compiled, analyzed, and presented properly. Keep clear and accurate records of data collected during experimentation. Data Analysis: Performs analyses and interpretation of the data where appropriate. Immunology: Design, prepare, conduct, and analyze complex experiments. May perform other duties as assigned. Position responsibilities: Reaches preliminary scientific conclusions related to research planning. Interacts with the PI, other lab members, and EHS officers to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. Interacts with external contacts such as staff at biotechnology and reagent companies to consult on research methods. Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning. Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority.</p> <p>Required Skills and Abilities</p> <ol> <li> <p>Ability to recommend the design and implementation of procedures and protocols under the direction of a higher-level authority.</p> </li><li> <p>Ability to Analyze, develop and interpret scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports.</p> </li><li> <p>Organizational Skills: Ensures data results are compiled, analyzed, and presented properly.</p> </li><li> <p>Independent Research: Performs independent research and laboratory techniques and participates in experimental research planning.</p> </li><li> <p>Team Collaboration: Ability to Coordinate with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. Ability to Interact with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments.</p> </li></ol> <p>Preferred Skills and Abilities</p> <p>Bachelor's or Master's degree in Biochemistry, Biophysics, Immunology, Molecular Biology, Biological Science or another directly related scientific field; 1+ years of hands-on experience working in a biology research lab.</p> <p>Principal Responsibilities</p> <ol> <li>Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority. 2. Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning 3. Ensures data results are compiled, analyzed, and presented properly. 4. Analyzes, develops and interprets scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports. 5. Performs independent research and laboratory techniques and participates in experimental research planning. 6. Interacts with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory. 7. Interacts with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments. 8. May perform other duties as assigned. Required Education and Experience Master's Degree in a scientific discipline and one year experience or an equivalent combination of education and experience. </li></ol> <p>Background Check Requirements</p> <p>All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.</p> <p>Health Requirements</p> <p>Certain positions have associated health requirements based on specific job responsibilities. These may include vaccinations, tests, or examinations, as required by law, regulation, or university policy.</p> <p>Posting Disclaimer</p> <p>Salary offers are determined by a candidate's qualifications, experience, skills, and education in relation to the position requirements, along with the role's grade profile and current internal and external market conditions.</p> <p>The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties through their hiring department.</p> <p>The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual's sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.</p> <p>Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).</p> <p>Note</p> <p>Yale University is a tobacco-free campus.</p>