<p>Supervise and develop a high-performing team of 3 full-time employees (1 direct report) and contractors based in Cambridge, MA, as well as assist with expanding the team in the near future. Oversee the monthly, quarterly, and annual close processes for $1B+ of operating expenses, including expense allocations, and non-operating items in accordance with U.S. GAAP; identify opportunities for improvement to scale for growth. Oversee foreign currency matters, including revaluation and translation adjustments. Oversee accounting for a $1B+ portfolio of debt securities. Collaborate with the Facilities and Capital Projects teams and oversee accounting for fixed assets and leases. Collaborate with FP&A, tax, and treasury to ensure actuals align with forecasts; reconcile U.S. GAAP versus management reporting variances. Support the external reporting process, coordinating with the SEC reporting team to ensure that key inputs are provided timely. Serve as the primary liaison with external and internal auditors to ensure smooth and efficient audit processes. Ensure internal controls over financial reporting operate effectively in accordance with SOX requirements. Identify and implement opportunities to automate and streamline manual processes. Collaborate with the technical accounting team on complex accounting transactions. Collaborate with ex-US accounting team as applicable to provide cross-functional support and seek opportunities to standardize processes globally. Implement the best financial and accounting practices for all locations, and benchmark external and internal operations. Provide accounting insight and support to executive management, including recommendations on unusual or complex transactions. Drive staff development and succession planning through mentorship, training, and knowledge transfer. Lead and support ad hoc projects and analyses, as assigned by senior leadership. Bachelor's degree in accounting required and/or Master's degree preferred. Minimum of 6 years of relevant experience in public accounting and/or private industry is required. CPA license required. Deep knowledge of U.S. GAAP and SOX compliance required. Global clinical and commercial biotech experience preferred. SAP experience strongly preferred. Must have strong analytical and organizational skills Detail-oriented with both the ambition and willingness to dive into the details Ability to work with cross-functional teams Self-motivated, proactive and able to quickly adapt to change Must be comfortable working both independently and in a team environment Proficiency in Microsoft Office applications, particularly Excel Able to handle multiple assignments and manage competing priorities with tight deadlines High degree of professionalism Ability to work sensitively with confidential material Strong interpersonal (verbal and written) communication skills Ability to communicate with various levels of management Decision-making, problem-solving, and analytical skills</p>